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THERE IS A HIDDEN RISK
CALLED LATENT TB INFECTION

Active Tuberculosis (TB) develops from Latent TB Infection (LTBI),
the dormant form of tuberculosis

LTBI is a global problem

1 in 4 people of the world's population has LTBI1

TB is one of the top ten causes of death globally

1 600 000

deaths from TB each year2

LTBI A THREAT TO BE WARY OF

LTBI A THREAT


TO BE WARY OF

Latent TB Infection
Latent TB

Latent TB is the name for the stage where TB bacteria have entered the body and become established, but are lying dormant not causing any symptoms. If they become active and start growing, then Latent TB turns into active TB disease.

LTBI is a Priority
Testing options for LTBI

If required, your doctor can perform two simple tests for LTBI - either a skin test or a blood test.

The END TB Strategy
End TB strategy and LTBI

The End TB strategy is a WHO initiative. Reducing TB deaths by 95% and new cases by 90% between 2015 and 2035 are 2 of its key priorities.

SOME POPULATIONS ARE MORE AT RISK

Most people with LTBI are unaware of the danger
that may have already quietly settled in them

healthy lungs
Healthy

You don't have any TB infection

Breathing in bacteria from person with active TB

healthy lungs
LTBI

You do not feel sick and you have no symptoms

Risk of progression

healthy lungs
Active TB

LTBI can become active TB, making you ill and risking infection for those you live with

IN 10

10% of people
with LTBI develop active TB during their lifetime3

For some people
the risk is much higher than 10%

UP TO 3 X MORE RISK3

Children
father and son are happy

Those < 5 years old have increased risk

FROM 16 TO 46 X MORE RISK3

Close contact
Two close persons

Living with a person with active TB increases risk

FROM 80 TO 110 X MORE RISK3

People living with HIV
image of people wearing hiv solidarity ribbon

Risk is dramatically increased in this community

FROM 8 TO 300 X MORE RISK3

All other immuno-suppressed
immuno-suppressed person in hospital

Such as those undergoing transplant, with kidney disease, treated with TNF-alpha inhibitors

UP TO 3 X MORE RISK3

Children
father and son are happy

Those < 5 years old have increased risk

FROM 16 TO 46 X MORE RISK3

Close contact
Two close persons

Living with a person with active TB increases risk

FROM 80 TO 110 X MORE RISK3

People living with HIV
image of people wearing hiv solidarity ribbon

Risk is dramatically increased in this community

FROM 8 TO 300 X MORE RISK3

All other immuno-suppressed
immuno-suppressed person in hospital

Such as those undergoing transplant, with kidney disease, treated with TNF-alpha inhibitors

These people have a high risk
of ltbi becomming active tuberculosis
Talk to your doctor today about LTBI

THEY WERE CONFRONTED BY LTBI

THEY WERE CONFRONTED

BY LTBI

3 years old, South Africa

39 years old, South Africa

35 years old, India

MEET MAYA AND HER MOTHER JASMIN

Jasmin knew that Maya had contact with people who had TB, but like many mums, Jasmin didn't worry about a condition that didn't give her Maya any symptoms...

... and then she was told her daughter had TB

MEET ADEBISI

Like many people, he knew about TB but did not worry about it, and like most people, he figured those things only happen to others...

... until he learned about LTBI

MEET KAUSAR

Like most people, Kausar wasn't eager to find out if she had an infection that could potentially become deadly...

... until she decided she would not be a victim

Watch the videos to learn more

High-risk populations for TB
Active & Latent Tuberculosis

THERE ARE OPTIONS TO TREAT IT

You don't have to wait to find out if you have Latent TB,
ask your doctor to arrange a test.

If your test is positive and you are diagnosed with LTBI,
don't worry there are several treatment options.

There are several
treatment options

The treatments needs to:

  • effectively treat LTBI with limited side effects
  • be convenient to take
  • be easy for you to complete
Treatment
regimen
6-9H
4R
3-4RH
3HP
Length of
Treatment
6-9 months
4 months
3-4 months
3 months
Schedule
Once a day
Once a day
Once a day
Once a week
How many
Intake
180-270
120
90-120
12

Completing your LTBI treatment today helps prevent active TB from developing in the future

SANOFI A LONG-TERM CONTRIBUTOR
IN FIGHTING TUBERCULOSIS

physician and patient

Since the 1950s, with the discovery of rifamycins, still today the cornerstone of tuberculosis (TB) treatment, Sanofi has had a sustained contribution to the fight against tuberculosis. We are committed to help reach the objective to end TB epidemic by 2030*.

The United Nations High Level Meeting in New York in September 2018 and the Global Fund Replenishment in October 2019 create the momentum to accelerate progress towards ending TB.

We at Sanofi believe that efficiently eliminating TB cannot be achieved without an integrated strategy, including the treatment of latent TB (LTBI) in high risk populations. People living with HIV & TB contacts are among those most at risk.

Together with our partners, we are stepping up the fight against TB by launching a Global Commitment:

  • Global LTBI awareness campaign
  • New resources and tools to improve education
  • Bold partnerships and support for TB prevention and care
  • New therapeutic approaches and adapted formulations for all populations

Together we can eliminate TB once and for all!

*United Nations Sustainable Development Goals 3.3
close video

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